Abstract: Melkersson-Rosenthal syndrome (MRS) is a rare syndrome involving nerve, skin, and mucosal, which characterized by a triad of recurrent oral facial swelling, recurrent peripheral facial paralysis, and cracked tongue. The classical manifestation is only found in 8%~25% of patients, so MRS is always misdiagnosed. Herein, we report three cases of classical MRS cases.

Key words: Melkersson-Rosenthal syndrome, cheilitis granulomatosa, facial paralysis, lingua plicata