Abstract: A 65-year-old male presented with papules, nodules and ulceration on the back of the right hand for more than 6 months without any obvious cause. The patient had been treated with erythromycin ointment and oral cefixime, but the effect was not good. Dermatological examination showed edematous erythema and herpetic herps on the back of the right hand, partially ruptured and formed ulcers. Histopathology indicated inflammatory granulation tissue hyperplasia, tissue acid-fast staining was positive, and high-throughput gene examination indicated hemophilus infection. Levofloxacin, clarithromycin and rifampicin were treated together with local debridement. The skin lesions basically subsided after 2 months of the treatment, and the skin lesions healed without recurrence after 6 months' treatment.

Key words: non-tuberculous mycobacterium, Mycobacterium haemophilum