China Journal of Leprosy and Skin Diseases ›› 2016, Vol. 32 ›› Issue (2): 74-76.

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Detection of serum level of IL-37 and IL-38 in the patients with early syphilis

ZHANG Shengjia, LI Furong, LIU Danxuan, WEN Jing, LI Zhen, XIAO Hailu, LI Zhongwei, ZHENG Rongtao, HOU Jianling, TIAN Hongqing   

  1. 1. School of Medical and Life Science, University of Jinan, Jinan 250062, China; 2. Shandong Provincial Institute of Dermatology and Venereology, Jinan 250022, China
  • Online:2016-02-15 Published:2020-09-17
  • Contact: TIAN Hongqing, E-mail: tianhq2006@126.com

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Abstract: Objective: To detect the serum level of IL-37 and IL-38 in the patients with early syphilis. Methods:The level of IL-37 and IL-38 was detected with ELISA in 140 patients with early syphilis and 180 healthy controls. Results: The medians of IL-37 and IL-38 in patients of early syphilis were 14.15 pg/mL and 12.21 pg/mL, which was lower than those of in healthy controls 31.76 pg/mL and 17.09 pg/mL (P<0.05). Conclusion: The level of IL-37 and IL-38 is lower in the patients with early syphilis, indicating that IL-37 and IL-38 may be involved in the cellular immunity.

Key words: early syphilis, interleukin-37, interleukin-38