Abstract: Objective：To assess the efficacy and safety of targeted UVB in the treatment of childhood vitiligo. Methods：Fifty lesions in 40 children with vitiligo were treated with targeted UVB (DualightTM UV 120-2 targeted phototherapy system), 1~2 times per week and the efficacy was assessed after 6-month treatment. Results：The total effective rate and cure rate were 62% and 26%, respectively. The effective rates of head and face, trunk, limbs and acral areas were 81.8%, 83.3%, 37.5% and 0, respectively. There was no obvious adverse in all patients. Conclusion：Targeted UVB is safe and effective in the treatment of vitiligo in children and the therapeutic effect relates to the location of lesions.

Key words: targeted UVB, childhood vitiligo