Abstract: Clinicopathological features of 213 patients with Atopic dermatitis (AD) were analyzed. The average age at onset was 0.88±1.73 years. 85.9% of the patients presented with chronic dermatitis and 85.9% patients had personal or family history of allergic diseases. Biopsy showed hyperkeratosis, small blister, acanthosis, spongiosis, infiltration of neutrophils and eosinophils around superficial vessels.