Abstract: Objective: To detect the levels of neutrophil-to-lymphocyte ratio (NLR), erythrocyte sedimentation rate (ESR) and white blood cell count (WBC) to help diagnosis of Henoch-Sch?nlein purpura (HSP) with viscera damage. Methods: A total of 46 patients were collected, including 32 HSP of simplex type and 44 HSP with viscera damage. The levels of NLR, ESR, WBC were detected. Results: (1) NLR in the patients with HSP with viscera damage was significantly higher than that in the patients with simple HSP patients (P<0.05). (2) The areas under the receiver operating characteristic (ROC) curve of NLR for the diagnosis of HSP with viscera damage was 0.708 (P <0.05). (3) NLR was associated with the white blood cell count (r=0.486, P<0.001). Conclusion: NLR is a potential clinical indicator for diagnosis and prognosis for HSP with viscera damage.

Key words: Henoch-Sch?nlein purpura(HSP), neutrophil-to-lymphocyte ratio(NLR), white blood cell count(WBC), hematological indices