China Journal of Leprosy and Skin Diseases ›› 2021, Vol. 37 ›› Issue (7): 454-455.doi: 10.12144/zgmfskin202107454

• Case Reports • Previous Articles     Next Articles

Deep ‘benign’ fibrous histiocytoma: a case report

LI Sitong1,2, WU Yatong2, WANG Ying2, BAI Yanping2   

  1. 1 Department of Dermatology, China-Japan Friendship Hospital, Beijing 100029, China; 
    2 Clinical Institute of China-Japan Friendship Hospital, Peking Union Medical College Graduate School, Beijing 100029, China
  • Online:2021-07-15 Published:2021-06-25
  • Contact: BAI Yanping, E-mail: zhi@tsinghua.edu.cn

Abstract: Deep “benign” fibrous histiocytoma(DBFH)is a rare benign fibrous tumour which most commonly arise in subcutaneous tissue. We report a 56-year-old female who presented with a painless nodule on her left arm for 4 years. Histopathology examination showed a solitary oval and well-defined borders subcutaneous tumour with fibrous pseudocapsule. The dimensions of tumour were about 1.8 cm×1.3 cm×0.6 cm, composed of bland ovoid to spindle cells arranged in a storiform pattern and with no atypia. Immunohistochemistry demonstrated CD34 positive, αSMA partially positive, and non-expression for Desmin, Stat6 and KP-1. Ki-67 presented a level of proliferation index of about 2%. The diagnosis of DBFH was made and the nodule was completely excised with no recurrence for 16 months.