Abstract: Cytophagic histiocytic panniculitis (CHP) is a rare clinical disease characterized by nodular lobular panniculitis of subcutaneous adipose tissue. A 56-year-old male presented with recurrent painful erythema and nodules on both lower and upper limbs, with fever, abnormal increase in white blood cells, and overall weakness. Antibiotic treatment was ineffective. Pathological biopsy showed the presence of “beanbag cells” in the dermis, ultimately leading to a definitive diagnosis of cytophagic histiocytic panniculitis. After glucocorticoid treatment, the patient's rash and symptoms rapidly improved.

Key words: cytophagic histiocytic panniculitis, subcutaneous panniculitis-like T-cell lymphoma, nodular panniculitis, Weber Christian Disease