China Journal of Leprosy and Skin Diseases ›› 2025, Vol. 41 ›› Issue (10): 744-747.doi: 10.12144/zgmfskin202510744

• Case Reports • Previous Articles     Next Articles

Allergic vasculitis complicated with myelodysplastic syndrome: a case report

QIN Yang1, FENG Jianglong2, ZHANG Wei1, ZHU Yiwei1, Cai Linglong1, ZHANG Guoqing1, LU Hongguang1   

  1. 1 Department of Dermatology, Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China; 2 Department of Pathology, Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China
  • Online:2025-10-15 Published:2025-09-29

Abstract: In addition to hematological manifestations, myelodysplastic syndromes (MDS) may also present with skin-related symptoms. Neutrophilic dermatoses are relatively common in MDS patients, while concurrent cutaneous vasculitis is rare, which may easily lead to delayed diagnosis. This paper reports a case of a patient with allergic vasculitis complicated with myelodysplastic syndrome. A 61-year-old female patient presented with dark purple erythema all over the body accompanied by pain for 3 months. Biopsy of the skin lesion on the right arm showed leukocytoclastic vasculitis. Routine blood tests revealed pancytopenia. Further bone marrow aspiration and biopsy confirmed the diagnosis of myelodysplastic syndrome. The patient was given 30mg of prednisone acetate tablets once a day. After 14 days of treatment, the skin rash subsided significantly. The patient was then referred to the hematology department for further treatment of myelodysplastic syndrome.

Key words: allergic vasculitis, myelodysplastic syndromes