中国麻风皮肤病杂志 ›› 2020, Vol. 36 ›› Issue (3): 171-173.doi: 10.12144/zgmfskin202003171

• 病例报告 • 上一篇    下一篇

TNF-α拮抗剂治疗复发性疱疹样脓疱病一例

王娟娟,苏玉华,丁瑜洁,冷红,季江,施辛   

  1. 苏州大学附属第二医院皮肤科，苏州，215004
  • 出版日期:2020-03-15 发布日期:2020-03-30
  • 通讯作者: 季江,E-mail: jijiang2222@126.com

Recurrent impetigo herpetiformis treated with TNF-α antagonist: a case report

WANG Juanjuan, SU Yuhua, DING Yujie, LENG Hong, JI Jiang, SHI Xin   

  1. Department of Dermatology, the Second Affiliated Hospital of Soochow University, Suzhou 215004, China
  • Online:2020-03-15 Published:2020-03-30
  • Contact: JI Jiang, E-mail: jijiang2222@126.com

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摘要： 患者，女，31岁。妊娠期反复脓疱加重1个月。患者8年前妊娠期曾全身出现红斑、脓疱，产后皮损自行消失。根据患者既往病史、症状、体征及辅助检查，诊断“疱疹样脓疱病”，入院后予TNF-α拮抗剂皮下注射，辅以复方甘草酸苷、阿奇霉素抗炎及外用药治疗，1周后患者皮疹明显好转出院。

关键词: 疱疹样脓疱病, TNF-α拮抗剂

Abstract: A 31-years-old female patient presented with widespread erythema and pustules during pregnancy, aggravating for 1 month. The patient had a history of the similar symptoms during pregnancy before 8 years ago and the lesions disappeared spontaneously after delivery. According to the patient's previous medical history, symptoms, physical signs and laboratory examination, the diagnosis of “impetigo herpetiformis” was made. The patient was injected subcutaneously with TNF-α antagonist, supplemented with Minol, Azithromycin anti-inflammatory and topical medication. The lesion was significantly improved after one week treatment.

Key words: impetigo herpetiformis, TNF-α antagonist