中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (7): 456-458.doi: 10.12144/zgmfskin202107456

• 病例报告 • 上一篇    下一篇

眼周局限性大疱性类天疱疮一例

薛晓彤,孙勇虎,周桂芝,张福仁   

  1. 山东第一医科大学附属皮肤病医院（山东省皮肤病医院，山东省皮肤病性病防治研究所），济南,250022
  • 出版日期:2021-07-15 发布日期:2021-06-25
  • 通讯作者: 张福仁，E-mail: zhangfuren@hotmail.com

Localized bullous pemphigoid around the eyes: a case report

XUE Xiaotong, SUN Yonghu, ZHOU Guizhi, ZHANG Furen   

  1. Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University, Jinan 250022, China
  • Online:2021-07-15 Published:2021-06-25
  • Contact: ZHANG Furen, E-mail: zhangfuren@hotmail.com

PDF (PC)

187

摘要： 患者，女，12岁。眼周反复红斑、水疱4个月，伴瘙痒。皮损组织病理示：表皮下水疱，真皮浅层淋巴细胞、嗜酸粒细胞、中性粒细胞等炎性细胞浸润。直接免疫荧光（DIF）：表皮基底膜IgG、C3阳性线状沉积。ELISA检测：血清抗BP230抗体 2.6 U/mL，抗BP180抗体阴性。诊断：局限性大疱性类天疱疮。予以甲泼尼龙、氨苯砜、吗替麦考酚酯治疗，目前在随访中。

Abstract: A 12-years-old girl presented with itching patches and blisters around her eyes for 4 months. Histopathological examination showed subepidermal blisters and lymphocytes, eosnophils and neutrophils infiltration in the superficial dermis. Direct immunofluorescence showed a positive of IgG and C3 along the basal membrane band. The level of anti-BP230 antibody was 2.6 U/mL and anti-BP180 antibody was negative. Diagnosis of localized bullous pemphigoid was made. The treatment of methylprednisolone, mycophenolate mofetil and dapsone was given and the patient is under follow-up.