中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (11): 748-752.doi: 10.12144/zgmfskin202111748

• 综述 • 上一篇    

反应性肉芽肿性皮炎的分类及临床研究进展

曾蕊,徐秀莲   

  1. 中国医学科学院 北京协和医学院 皮肤病医院 皮肤病研究所，南京，210042
  • 出版日期:2021-11-15 发布日期:2021-09-15
  • 通讯作者: 徐秀莲，E-mail: xxlqjl@sina.com

The classification and clinical advance of reactive granulomatous dermatitis

ZENG Rui, XU Xiulian   

  1. Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
  • Online:2021-11-15 Published:2021-09-15
  • Contact: XU Xiulian, E-mail:xxlqjl@sina.com

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摘要： 反应性肉芽肿性皮炎包括栅栏状中性粒细胞性肉芽肿性皮炎、间质性肉芽肿性皮炎及间质性肉芽肿性药物反应三类疾病。其病因及发病机制尚不明确，临床及组织病理表现多样，常伴有系统性疾病如类风湿关节炎和系统性红斑狼疮。本文综述了这三类疾病的发病机制、临床和病理特点、诊断和治疗等。

关键词: 反应性肉芽肿性皮炎, 栅栏状中性粒细胞肉芽肿性皮炎, 间质性肉芽肿性皮炎, 间质性肉芽肿性药物反应

Abstract: Reactive granulomatous dermatitis (RGD) is consisting of palisaded neutrophilic granulomatous dermatitis (PNGD), interstitial granulomatous dermatitis (IGD) and interstitial granulomatous drug reaction (IGDR). The etiology and pathogenesis of RGD remain unclear and the clinical and histopathological manifestations are varied. RGD usually associated with underlying systemic diseases such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The pathogenesis, clinical and pathological characteristics, diagnosis and treatment of these three types of diseases are reviewed in this paper.

Key words: reactive granulomatous dermatitis；palisaded neutrophilic granulomatous dermatitis, interstitial granulomatous dermatitis, interstitial granulomatous drug reaction