中国麻风皮肤病杂志 ›› 2022, Vol. 38 ›› Issue (2): 118-119.doi: 10.12144/zgmfskin202202118

• 病例报告 • 上一篇    下一篇

误诊为寻常疣的二期梅毒一例

南海峰1,董国英2   

  1. 1衡水市第二人民医院皮肤科，河北衡水，053000;2衡水学院，河北衡水，053000
  • 出版日期:2022-02-15 发布日期:2021-12-22
  • 通讯作者: 董国英，E-mail: nhfdgy@163.com

Secondary syphilis misdiagnosed as verruca vulgaris: a case report

NAN Haifeng1, DONG Guoying2   

  1. 1 The Second People's Hospital of Hengshui City, Hengshui 053000, China; 2 Hengshui College, Hengshui 053000, China
  • Online:2022-02-15 Published:2021-12-22
  • Contact: DONG Guoying, E-mail: nhfdgy@163.com

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摘要： 患者，女，42岁。双手掌多发斑丘疹45天。曾按寻常疣治疗效果不佳。皮损组织病理：表皮角化过度伴角化不全，棘层肥厚，真皮浅层可见大量淋巴细胞和浆细胞。实验室检查：TPPA（+），RPR 1:64（+）。诊断：二期梅毒。予以苄星青霉素240万U治疗，每周1次，治疗3次皮损消退。

关键词: 二期梅毒, 寻常疣, 误诊

Abstract: A 42-year-old female presented with multiple maculopapular rashes on her palms for 45 days. She was misdiagnosed as verruca vulgaris and given the corresponding treatment with no improvement. Histopathologic examination revealed epidermal hyperkeratosis accompanied by parakeratosis, acanthosis and a large number of lymphocytes and plasmocytes were found in the upper dermis. Laboratory examination showed positive TPPA and the titre of RPR was 1:64. The case was diagnosed as secondary syphilis and was treated with an intramuscular injection of benzathine, 2.4 million units, once a week. The skin lesions subsided after 3-week treatment.

Key words: secondary syphilis, common wart, misdiagnosis