中国麻风皮肤病杂志 ›› 2022, Vol. 38 ›› Issue (8): 549-552.doi: 10.12144/zgmfskin202208549

• 病例报告 • 上一篇    下一篇

以眼睑和头皮红斑为表现的早期皮肤型红斑狼疮一例

魏腾超,周桂芝,施仲香,刘红   

  1. 山东第一医科大学附属皮肤病医院(山东省皮肤病医院)，山东省皮肤病性病防治研究所，山东济南，250022
  • 出版日期:2022-08-15 发布日期:2022-06-22

Early cutaneous lupus erythematosus characterized by erythema of the eyelids and scalp: a case report

WEI Tengchao, ZHOU Guizhi, SHI Zhongxiang, LIU Hong   

  1. Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2022-08-15 Published:2022-06-22

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摘要： 患者，女，29岁。左眼睑红斑3个月，发现头皮脱发区1天。头皮组织病理：表皮轻度角化过度，基底细胞灶性液化变性，真皮浅层血管周围少许单一核细胞浸润，真皮内毛囊数量明显减少，真皮深层毛囊及附属器周围较多淋巴细胞浸润。免疫荧光：表皮基底膜C3、IgM、IgA弱阳性带状沉积，IgG阴性。阿新蓝染色:胶原间黏蛋白沉积。诊断为皮肤红斑狼疮。给予硫酸羟氯喹片口服、他克莫司软膏和卤米松软膏外用治疗，红斑消退。

关键词: 皮肤型红斑狼疮, 眼睑红斑

Abstract: A 29-year-old female presented with erythmia on the left eyelid for more than 3 months and hair loss area found on scalp for 1 day, ANA and RNP/Sm were all positive, pathological examination showed mild hyperkeratosis of the epidermis, focal vacuolar alteration of the basal cell layer, lymphocytes infiltrate around deep dermis and appendages. Immunofluorescence: epidermal basement membrane C3, IgM, IgA weakly positive banded deposition, IgG negative. Collagen intermucin deposition. The case was diagnosed as cutaneous lupus erythematosus and was treated with oral hydroxychloroquine, topical tacrolimus and halometasone ointment. The erythema subsided and the condition of the case improved.

Key words: cutaneous lupus erythematosus, alopecia, eyelid erythema