中国麻风皮肤病杂志 ›› 2022, Vol. 38 ›› Issue (8): 558-561.doi: 10.12144/zgmfskin202208558

• 病例报告 • 上一篇    下一篇

司库奇尤单抗治疗伴甲损害的寻常型银屑病一例

游紫梦,刘宏杰,杨礼凤,闫薇   

  1. 四川大学华西医院皮肤性病科，成都，610041
  • 出版日期:2022-08-15 发布日期:2022-06-23

Psoriasis vulgaris with nail change treated with secukinumab: a case report

YOU Zimeng, LIU Hongjie, YANG Lifeng, YAN Wei   

  1. Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu 610041, China
  • Online:2022-08-15 Published:2022-06-23

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摘要： 患者，男，38岁。头皮、腋下红斑脱屑，手足甲增厚变色1年余。皮肤科查体：头皮、双侧腋下可见红斑，部分红斑上可见细小鳞屑；双手足部分甲板远端甲分离、甲下角化过度，甲变色，甲板表面可见点状凹陷。诊断为寻常型银屑病、甲银屑病。给予司库奇尤单抗治疗，皮损迅速消退，指/趾甲损害显著改善。随访1年未见皮损反复及明显不良反应。

关键词: 甲银屑病, 司库奇尤单抗

Abstract: A 38-year-old male presented with erythema with scales on scalp and armpit, fingernails and toenails thickening and discoloration for more than 1 year. Physical examination showed erythema with small scales on scalp and armpit, onycholysis, distal subungual hyperkeratosis, discoloration and pitting on part of nails. Diagnosis of psoriasis vulgaris and nail psoriasis were made and the patient was treated with secukinumab. Lesions disappeared rapidly and obvious improvement was seen in nails changes. No obvious adverse effect and no relapse of skin lesions were seen in 1-year follow-up.

Key words: nail psoriasis, secukinumab