中国麻风皮肤病杂志 ›› 2022, Vol. 38 ›› Issue (9): 629-631.doi: 10.12144/zgmfskin202209629

• 病例报告 • 上一篇    下一篇

复发性线状棘层松解性皮病一例

贾凤铭1,2,刘永霞,杨青1,卢宪梅   

  1. 1 山东第一医科大学附属皮肤病医院( 山东省皮肤病医院)，山东省皮肤病性病防治研究所,济南，250022; 2山东第一医科大学(山东省医学科学院)，山东济南，250117
  • 出版日期:2022-09-15 发布日期:2022-07-13

Relapsing linear acantholytic dermatosis: a case report

JIA Fengming1,2, LIU Yongxia1, YANG Qing1, LU Xianmei1   

  1. 1 Shandong Provincial Hospital for Skin Diseases ＆ Shandong Provincial Institute of Dermatology and Venereology，Shandong First Medical University ＆ Shandong Academy of Medical Sciences，Jinan 250022，China; 2 Shandong First Medical University ＆ Shandong Academy of Medical Sciences, Jinan 250117，China
  • Online:2022-09-15 Published:2022-07-13

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摘要： 复发性线状棘层松解性皮病是一种比较少见的疾病。患儿，女，6岁。右侧臀部、股后红色斑块反复5年余，加重2个月。皮肤科检查：右侧臀、股后部、腘窝见条索状分布的暗红色斑块，上覆白色鳞屑，局部结血痂，散见色素沉着斑，皮损沿Blaschko线分布。组织病理学检查示：表皮角化过度、角化不全，棘层松解呈砖墙倒塌样。直接免疫荧光（DIF）阴性。

关键词: 复发性, 线状棘层松解, Blaschko线

Abstract: Relapsing linear acantholytic dermatosis is a rare disease. We report a case of relapsing linear acantholytic dermatosis. A six-year-old girl presented with recurrent erythematous and plaque on the right hip and posterior thigh for 5 years, with aggravation for 2 months. Linear erythematous plaques with overlying white scale and localized bloody scrab was on her right hip, right posterior thigh and popliteal fossa, and pigmentation scattered was seen. The lesion distributed along with the Blaschko line. Histopathological examination showed hyperkeratosis as well as parakeratosis, acantholysis like a collapsed wall. Direct immunofluorescence (DIF) showed negative result.

Key words: relapsing, linear acantholysis, Blaschko line