中国麻风皮肤病杂志 ›› 2023, Vol. 39 ›› Issue (5): 369-371.doi: 10.12144/zgmfskin202305369

• 病例报告 • 上一篇    下一篇

渐进性坏死性黄色肉芽肿一例

王攀攀1,钟绍烤2,汤晨昱1,赵一格1,王彦红3,沈宏3,王平3   

  1. 1浙江中医药大学附属杭州第三人民医院皮肤科，浙江杭州，310009；
    2杭州市第三人民医院眼科，浙江杭州，310009；
    3杭州市第三人民医院皮肤科，浙江杭州，310009
  • 出版日期:2023-05-15 发布日期:2023-05-16

Necrobiotic xanthogranuloma: a case report

WANG Panpan1, ZHONG Shaokao2, TANG Chenyu1, ZHAO Yige1, WANG Yanhong3, SHEN Hong3, WANG Ping3   

  1. 1 Department of Dermatology, Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou 310009, China;
    2 Department of Ophthalmology, Hangzhou Third People’s Hospital, Hangzhou 310009, China;
    3 Department of Dermatology, Hangzhou Third People’s Hospital, Hangzhou 310009, China
  • Online:2023-05-15 Published:2023-05-16

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摘要： 患者，女，50岁。双眼眶周黄褐色增生性肿物10年余。皮肤科检查可见左眼眶周及右眼眶内、外侧有黄褐色增生性肿物，表面轻度毛细血管扩张，触之坚实，边界清楚。眼科检查发现左眼视网膜色素上皮脱离。实验室检查发现贫血、血小板减少，血清免疫电泳无异常。组织病理示真皮及皮下组织弥漫淋巴细胞、上皮样细胞、泡沫样组织细胞浸润，可见局灶性坏死。诊断为渐进性坏死性黄色肉芽肿。

关键词: 渐进性坏死性黄色肉芽肿, 视网膜色素上皮脱离, 贫血, 血小板减少

Abstract: A 50-year-old female presented with yellowish brown proliferative tumor around the orbit of both eyes for more than 10 years. Dermatological examination showed that there were yellowish brown proliferative masses around the left orbit and inside and outside the right orbit, with mild telangiectasia on the surface, solid touch and clear boundary. Ophthalmic examination revealed retinal pigment epithelium detachment in the left eye. Laboratory examination found anemia and thrombocytopenia, and there was no abnormality in serum immunoelectrophoresis. Histopathology showed diffuse infiltration of lymphocytes, epithelioid cells and foam like cells in the dermis and subcutaneous tissues, and focal necrosis was seen. The diagnosis of necrobiotic xanthogranuloma was made.

Key words: necrobiotic xanthogranuloma, retinal pigment epithelium detachment, anemia, thrombocytopenia