中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (3): 210-212.doi: 10.12144/zgmfskin202503210

• 病例报告 • 上一篇    下一篇

卡式枝孢瓶霉致面部着色芽生菌病一例

陈悦,顾海萍   

  1. 相城区皮肤病医院皮肤科，江苏苏州，215100
  • 出版日期:2025-03-15 发布日期:2025-03-03

Chromoblastomycosis of face caused by Cladophialophora carrionii: a case report

CHEN Yue, GU Haiping   

  1. Department of Dermatology, Dermatology Hospital of Xiangcheng, Suzhou 215100, China
  • Online:2025-03-15 Published:2025-03-03

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摘要： 着色芽生菌病通常较难鉴定致病真菌的属种，本文报道卡式枝孢瓶霉致面部着色芽生菌病一例。患者，男，76岁。左眼下方红色斑块1年余。病理提示感染性肉芽肿改变。抗酸染色、PAS染色均为阴性。宏基因组二代测序（mNGS）检出卡氏枝孢瓶霉。口服伊曲康唑治疗3个月后皮损基本愈合，遗留瘢痕可进一步行手术治疗。

关键词: 卡式枝孢瓶霉, 着色芽生菌病, 伊曲康唑

Abstract: It is usually difficult to identify the genus and species of pathogenic fungi in chromoblastomycosis. This article reports a case of facial chromoblastomycosis caused by Cladophialophora carrionii. A 76-year-old male presented with red plaques under the left eye for more than 1 year. Biopsy showed infectious granuloma. Acid-fast staining and PAS staining were negative. Metagenomic next-generation sequencing (mNGS) showed Cladophialophora carrionii. After 3 months of oral itraconazole treatment, the skin lesions basically healed, and further surgical treatment can be carried out for the remaining scars.

Key words: Cladophialophora carrionii, chromoblastomycosis, itraconazole