中国麻风皮肤病杂志 ›› 2026, Vol. 42 ›› Issue (10): 691-693.doi: 10.12144/zgmfskin202610691

• 新发与再发感染性皮肤病 • 上一篇    下一篇

原发性皮肤诺卡菌病一例

宋霞璐1,2,周琼艳3   

  1. 1宁波大学医学部，浙江宁波，315211；2兰溪市人民医院皮肤科，浙江兰溪，321100；3宁波大学附属第一医院皮肤科，浙江宁波，315010
  • 出版日期:2026-10-15 发布日期:2026-10-09

Primary cutaneous nocardiosis: a case report

SONG Xialu1,2, ZHOU Qiongyan3   

  1. 1 Health Science Center, Ningbo University, Ningbo 315211, China; 2 Department of Dermatology, Lanxi People's Hospital, Lanxi 321100, China; 3 Department of Dermatology, The First Affiliated Hospital of Ningbo University, Ningbo 315010, China
  • Online:2026-10-15 Published:2026-10-09

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摘要： 患者，男，76岁，右上肢局部红肿疼痛1周。皮肤科查体：右前臂近肘关节处可见约8 cm×3 cm的皮肤红肿破溃，伴脓性分泌物，右上臂可见呈串珠样大小不一的红色结节。实验室检查示白细胞计数、超敏C反应蛋白升高，细菌培养提示巴西诺卡菌。诊断：原发性皮肤诺卡菌病。治疗：口服复方磺胺甲噁唑片及局部对症处理，治疗50天痊愈，随访半年未复发。

关键词: 原发性皮肤诺卡菌病, 巴西诺卡菌, 复方磺胺甲噁唑

Abstract: A 76-year-old male patient who presented with localized erythema, swelling, and pain in the right upper limb for one week. Dermatological examination revealed an approximately 8 cm×3 cm erythematous ulcer with purulent discharge near the right elbow joint, and beaded red nodules of varying sizes on the right upper arm. Laboratory tests showed elevated white blood cell count and hypersensitivity C-reactive protein. Bacterial culture yielcled positive for Nocardia brasiliensis. Diagnosis of primary cutaneous nocardiosis was made. The patient was administered oral trimethoprim sulfamethoxazole together with local symptomatic treatment. Complete recovery was achieved after 50 days of therapy, and no recurrence occurred during the six-month follow-up.

Key words: primary cutaneous nocardiosis, Nocardia brasiliensis, trimethoprim sulfamethoxazole