中国麻风皮肤病杂志 ›› 2016, Vol. 32 ›› Issue (4): 203-206.

• 论著 • 上一篇    下一篇

成人种痘样水疱病样EB病毒相关淋巴细胞增生性疾病3例

张秋鹂，汪 旸，涂 平   

  1. 北京大学第一医院皮肤科，北京，100034
  • 出版日期:2016-04-15 发布日期:2018-12-24
  • 通讯作者: 汪旸，E-mail：yangwang_dr@bjmu.edu.cn；涂平，E-mail：tup0207@sina.com

Hydroa vacciniforme-like EB virus-associated lymphoproliferative disorder in adults: three cases report

ZHANG Qiuli, WANG Yang, TU Ping   

  1. Department of Dermatology and Venerology, Peking University First Hospital, Beijing 100034, China
  • Online:2016-04-15 Published:2018-12-24
  • Contact: WANG Yang, E-mail:yangwang_dr@bjmu.edu.cn; TU Ping, E-mail：tup0207@sina.com

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摘要： 3例均为成年女性患者，全身可见对称性分布的红色丘疹、水疱、结节、坏死结痂及凹陷性瘢痕，伴有发热、淋巴结肿大等系统症状。组织病理学示真皮内淋巴样细胞浸润，部分围绕血管周围浸润。血清中EB病毒抗体IgG阳性，外周血淋巴细胞有高拷贝的EB病毒DNA。患者外周血免疫分型示异常成熟T细胞增生。

关键词: EB病毒, 种痘样水疱病样, 淋巴细胞增生性疾病

Abstract: Three female patients presented with red papules, blister, nodules, scab and depressed scar all over the whole body symmetrically, with systemic symptoms including fever and lymphadenectasis. Biopsy of the skin lesion showed dense infiltration constituting of lymphoid cells in dermis. High titers of IgG antibody to EBV antigen, high copies of EBV-DNA and abnormal lymphocyte immunotype were identified in the sera of the three patients.

Key words: EBV, hydroa vacciniforme-like, lymphoproliferative disorder