中国麻风皮肤病杂志 ›› 2017, Vol. 33 ›› Issue (5): 265-267.

• 论著 • 上一篇    下一篇

大光斑低能量Q开关1064 nm Nd:YAG 激光治疗雀斑

迟晓君1,2  史纹豪1,2  林燕2  郭璇2  耿建辉2  刘华绪2   

  1. 1济南大学 山东省医学科学院医学与生命科学学院,济南,250000
    2山东省皮肤病性病防治研究所,济南,250022
  • 出版日期:2017-05-15 发布日期:2018-12-19
  • 通讯作者: 刘华绪， E-mail: liueternal@163.com

Efficacy and safety assessments of large spot size, low-fluence Q-Switched 1064-nm neodymium-doped yttrium aluminum garnet laser in the treatment of facial freckles

CHI Xiaojun1,2, SHI Wenhao1,2, LIN Yan2, GUO Xuan2, GENG Jianhui2, LIU Huaxu2.   

  1. 1. School of Medicine and Life Sciences, University of Jinan-Shandong Academy of medicine Sciences, Jinan 250000, China; 
    2. Shandong Provincial Institute of Dermatology and Venereology, Jinan 250022, China
  • Online:2017-05-15 Published:2018-12-19
  • Contact: LIU Huaxu, E-mail: liueternal@163.com

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摘要： 目的：评价大光斑低能量模式Q开关1064 nm Nd:YAG激光治疗雀斑的疗效和安全性。方法：应用大光斑低能量模式Q开关1064 nm Nd:YAG激光治疗15例成人女性雀斑患者。治疗参数：波长1064 nm，脉宽10 ns，光斑7 mm，能量密度1.5~2.0 J/cm2，频率10 hz，每2~3周一次，治疗3~5次。末次治疗结束后随访6个月。结果：8例患者76%~100%皮损颜色变淡，4例51%~75%皮损颜色变淡，3例26%~50%皮损颜色变淡。所有患者治疗后仅有轻微红斑，数小时内消退，治疗后无色沉发生。随访6个月后2例患者复发。结论：大光斑低能量Q开关1064 nm Nd:YAG激光治疗雀斑安全有效。

关键词: 雀斑, Q开关1064 nm Nd:YAG激光

Abstract: Objective: To assess the efficacy of large spot size, low-fluence 1064 nm Q-switched neodymiumdoped yttrium aluminum garnet (QS Nd:YAG) laser in the treatment of facial freckles. Methods: Fifteen patients with facial freckles were treated with large spot size, 1064 nm QS Nd:YAG laser with wavelength of 1064 nm, pulse width of 10 ns, spot size of 7 mm, energy density of 1.5-2.0 J/cm2 and frequency of 10 Hz, once every 2-3 weeks for 3-5 times. The efficacy was assessed by two dependent dermatologists and the patients themselves. The patients were followed up for 6 months after the last treatment. Results: The color of 76%-100% lesions lightened in 8 patients, 51%-75% in 4, 26%-50% in 3. After treatment, all the cases presented with mild erythema which only lasted for several hours. The lesions relapsed in two patients after6 months of followed up. Conclusion: Large sport size, low-fluence 1064 nm QS Nd:YAG laser treatment is effective in the treatment of facial freckles.

Key words: freckles, low-fluence 1064 nm QS Nd:YAG laser