中国麻风皮肤病杂志 ›› 2017, Vol. 33 ›› Issue (5): 276-280.

• 论著 • 上一篇    下一篇

口服特比萘芬联合5-氨基酮戊酸光动力治疗淡紫拟青霉皮肤感染一例

王鑫1*  张韡2*  沈永年2  吕桂霞2  梅嬛2  蒋娟2   

  1. 1青岛大学附属青岛市妇女儿童医院皮肤科,青岛,266011
    2中国医学科学院北京协和医学院皮肤病医院,南京,210042 *共同第一作者
  • 出版日期:2017-05-15 发布日期:2018-12-19
  • 通讯作者: 蒋娟，E-mail: drjjiang@vip.163.com

Terbinafine combined with 5-aminolevulinic acid photodynamic therapy in the treatment of cutaneous Paecilomyces lilacinus infection: a case report

WANG Xin1, ZHANG Wei2, SHEN Yongnian2, LYU Guixia2, MEI Huan2, JIANG Juan2.   

  1. 1. Department of Dermatology, Qingdao Women and Children's Hospital,Qingdao University，Qingdao 266011,China; 
    2. Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
  • Online:2017-05-15 Published:2018-12-19
  • Contact: JIANG Juan, E-mail: drjjiang@vip.163.com

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摘要： 患者,女，46岁。因右上臂红斑伴瘙痒1年就诊。根据其临床症状和体征,受累组织器官中真菌的分离培养,组织病理学特征以及分子生物学鉴定技术，该病例诊断为淡紫拟青霉皮肤感染。体外药敏试验显示对特比萘芬敏感，采用5-氨基酮戊酸光动力联合口服特比萘芬治疗取得较为满意的治疗效果。

关键词: 淡紫拟青霉, 皮肤感染, 特比萘芬, 5-氨基酮戊酸光动力

Abstract: A 46 year-old woman presented with a pruritic erythema on the right upper arm for more than a year. The diagnosis of Paecilomyces lilacinus infection was made according to clinical manifestations, culture of the fungus, histological features of the lesions and molecular technique. The patient was sensitive to terbinafine and then treated with terbinafine combined with 5-aminolevulinic acid photodynamic therapy (ALA-PDT) and the efficacy was good. 

Key words: paecilomyces lilacinus, cutaneous infection, terbinafine, ALA-PDT