中国麻风皮肤病杂志 ›› 2022, Vol. 38 ›› Issue (3): 182-184.doi: 10.12144/zgmfskin202203182

• 病例报告 • 上一篇    下一篇

偶发分枝杆菌致感染性肉芽肿一例

陈祚玺1,2,王娜2,于长平2,施仲香2,潘晴2,暴芳芳2,卢宪梅2,王真真2,刘红2,张福仁2   

  1. 1山东大学齐鲁医学院，山东济南，250012;
    2山东第一医科大学附属皮肤病医院(山东省皮肤病医院)，山东省皮肤病性病防治研究所，济南，250022
  • 出版日期:2022-03-15 发布日期:2022-01-05
  • 通讯作者: 张福仁，E-mail: zhangfuren@hotmail.com

Infectious granuloma due to Mycobacterium fortuitum: a case report

CHEN Zuoxi1,2, WANG Na2, YU Changping2, SHI Zhongxiang2, PAN Qing2, BAO Fangfang2, LU Xianmei2, WANG Zhenzhen2, LIU Hong2, ZHANG Furen2   

  1. 1 Cheeloo College of Medicine, Shandong University, Jinan 250012, China;
    2 Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University, Jinan 250022, China
  • Online:2022-03-15 Published:2022-01-05
  • Contact: ZHANG Furen, E-mail: zhangfuren@hotmail.com

PDF (PC)

528

摘要： 患者，男，41岁。躯干、双侧大腿上部散在触痛性结节、斑块54天。发病前有大腿外伤史及河水接触史。皮肤组织病理检查示：真皮深部感染性肉芽肿改变。细菌培养及菌落DNA PCR测序示偶发分枝杆菌。患者行全外显子测序未发现免疫、感染相关突变,综上诊断为偶发分枝杆菌感染性肉芽肿。给予左氧氟沙星、克拉霉素、脓肿切开、穿刺引流等，病情好转。

关键词: 偶发分枝杆菌, 感染性肉芽肿, 全外显子测序

Abstract: A 41-year-old man presented with a 2-month history of scattered tender nodules, plaques in his trunk and lower limbs. Before the onset of lesions, he was injured on the lateral right thigh and swam in a river. Histopathological examination revealed a dermal infectious granuloma. Mycobacterium fortuitum was confirmed by bacteria identification and PCR. No immunological or infection-related mutation was found by whole exome sequencing. The diagnosis of infectious granuloma due to Mycobacterium fortuitum was made. The patient was treated with levofloxacin, clarithromycin, abscess incision, drainage etc., and the condition improved obviously.

Key words: Mycobacterium fortuitum, infectious granuloma, whole exome sequencing