中国麻风皮肤病杂志 ›› 2023, Vol. 39 ›› Issue (10): 755-757.doi: 10.12144/zgmfskin202310755

• 病例报告 • 上一篇    下一篇

Muir-Torre综合征一例

何芳1,陈怡雯1,陈其雷2,袁缘1,徐圣经1,张敏1   

  1. 1南京医科大学附属江宁医院皮肤科，江苏南京，211100；2南京医科大学附属江宁医院整形美容科，江苏南京，211100
  • 出版日期:2023-10-15 发布日期:2023-10-11

Muir-Torre syndrome: a case report

HE Fang1, CHEN Yiwen1, CHEN Qilei2, YUAN Yuan1, XU Shengjing1, ZHANG Min1   

  1. 1 Department of Dermatology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 211100, China; 2 Department of Plastic Surgery, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 211100, China
  • Online:2023-10-15 Published:2023-10-11

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摘要： Muir-Torre综合征是一种罕见的常染色体显性遗传病，是遗传性非息肉性结直肠癌（HNPCC）的亚型，临床上表现为至少一种内脏恶性肿瘤合并皮脂腺肿瘤，伴或不伴角化棘皮瘤。本文报道一例多发性皮脂腺癌患者，既往有肺腺癌病史，根据患者病史及组织活检，诊断为Muir-Torre综合征。

关键词: Muir-Torre综合征, 皮脂腺癌, 肺转移癌

Abstract: Muir-Torre syndrome is inherited in an autosomal dominant pattern and generally accepted as a variant of Hereditary Nonpolyposis Colorectal Cancer (HNPCC). And it is typically characterized by at least one visceral malignancy and one cutaneous neoplasm of sebaceous differentiation, with or without keratoacanthomas. We report a patient with multiple sebaceous carcinoma who had a history of lung adenocarcinoma. The diagnosis was confirmed by skin biopsy and previous medical history.

Key words: Muir-Torre syndrome, sebaceous carcinoma, metastasized lung cancer