中国麻风皮肤病杂志 ›› 2023, Vol. 39 ›› Issue (4): 248-252.doi: 10.12144/zgmfskin202304248

• 论著 • 上一篇    下一篇

皮肤偶发分枝杆菌感染二例并文献分析

米州洋,张雍,暴芳芳,刘永霞,陈声利,孙勇虎,张福仁   

  1. 山东第一医科大学附属皮肤病医院（山东省皮肤病医院），山东省皮肤病性病防治研究所，山东济南，250022
  • 出版日期:2023-04-15 发布日期:2023-03-27

Two cases of cutaneous Mycobacterium Fortuitum infection and literature review

MI Zhouyang, ZHANG Yong, BAO Fangfang, LIU Yongxia, CHEN Shengli, SUN Yonghu, ZHANG Furen   

  1. Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University, Jinan 250022, China
  • Online:2023-04-15 Published:2023-03-27

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摘要： 偶发分枝杆菌是一种广泛存在于自然环境的条件致病菌，具有一定的耐药性，常规抗生素治疗效果不佳。现报道皮肤偶发分枝杆菌感染2例，均经过病理及qPCR确诊，应用利福平、克拉霉素治疗4个月后皮损明显消退。本文还对既往报道的466例偶发分枝杆菌感染病例的临床特征进行分析，总结归纳偶发分枝杆菌感染的诊断和治疗特点。

关键词: 偶发分枝杆菌, 利福平, 克拉霉素

Abstract: Mycobacterium Fortuitum is an opportunistic pathogen widely existing in the natural environment. It has certain drug resistance, and conventional antibiotic treatment is not effective. Here, we reported 2 cases diagnosed as cutaneous Mycobacterium Fortuitum infection through routine pathology and qPCR. After treatment with rifampicin and clarithromycin for 4 months, the skin lesions subsided significantly. The literature were researched, and  the characteristics of diagnosis and treatment of 466 cases was analyzed.

Key words: Mycobacterium Fortuitum, rifampicin, clarithromycin