中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (6): 427-429.doi: 10.12144/zgmfskin202406427

• 病例报告 • 上一篇    下一篇

儿童C型淋巴瘤样丘疹病一例

杨远远1,刘霞2,索翠平3,管志强1,李永欣1,赵建斌1   

  1. 1徐州医科大学附属市立医院皮肤科，江苏徐州，221000；2徐州医科大学附属市立医院病理科，江苏徐州，221000；3徐州医科大学附属市立医院病案与数据统计中心，江苏徐州，221000
  • 出版日期:2024-06-15 发布日期:2024-05-08

Type C lymphomatoid papulosis in a child: a case report

YANG Yuanyuan1, LIU Xia2, SUO Cuiping3, GUAN Zhiqiang1, LI Yongxin1, ZHAO Jianbin1   

  1. 1 Department of Dermatology, Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University, Xuzhou 221000, China; 2 Department of Pathology, Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University, Xuzhou 221000, China; 3 Department of Medical Records and Data Statistics Center, Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University, Xuzhou 221000, China
  • Online:2024-06-15 Published:2024-05-08

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摘要： C型淋巴瘤样丘疹病较少见，本文报道一例。患者，男，13岁。全身反复红色丘疹结节2年，部分皮疹中央溃烂，系统检查未见异常，曾诊断为“急性痘疮样苔藓样糠疹”。入院后完善组织病理示：肿瘤真皮层和皮下组织可见形态一致的间变大淋巴细胞弥漫浸润。免疫组化：CD2(+++)，CD8(+)，CD30(+++)，GranzymeB(+)，Ki67(+90%)，TI-A(+)，TCR基因重排阳性。诊断：C 型淋巴瘤样丘疹病。

关键词: 淋巴瘤样丘疹病, 儿童, 免疫组织化学

Abstract: Type C lymphomatoid papulosis is rare, herein we report a case in this paper. A 13-year-old boy presented with recurrent red papular nodules all over the body for 2 years, with partial nodules breaking down in the central. Physical examination showed no abnormalities, and he was early diagnosed as pityriasis lichenoides et varioliformis acuta. Histopathological biopsy showed diffuse infiltration of large anaplastic lymphocytes with consistent morphology in the dermis and subcutaneous tissue of the tumor. Immunohistochemical showed CD2 (+++), CD8 (+), CD30 (+++), GranzymeB (+), Ki67 (+ 90%), TI-A(+) , test positive for TCR gene rearrangement. The dignosis of type C lymphomatoid papulosis was finally made.

Key words: lymphomatoid papulosis, children, immunohistochemistry