中国麻风皮肤病杂志 ›› 2026, Vol. 42 ›› Issue (4): 292-298.doi: 10.12144/zgmfskin202604292

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化脓性汗腺炎的疼痛管理

邵静雅1,2,林昭萍3,4,5,吴晓婷1,2,陈雨珊1,2,郝明悦1,2,沈长兵3,4,5,高静1,2   

  1. 1安徽医科大学第二附属医院皮肤与性病科，安徽合肥，230601；2安徽医科大学第二附属医院等离子体应用联合实验室，安徽合肥，230601；3北京大学深圳医院皮肤性病科，广东深圳，518036；4深圳北京大学-香港科技大学医学中心皮肤病研究所，广东深圳，518036；5汕头大学医学院北大深圳临床学院，广东深圳，518036
  • 出版日期:2026-04-15 发布日期:2026-04-08

Pain management for hidradenitis suppurativa

SHAO Jingya1,2, LIN Zhaoping3,4,5, WU Xiaoting1,2, CHEN Yushan1,2, HAO Mingyue1,2, SHEN Changbing3,4,5, GAO Jing1,2   

  1. 1 Department of Dermatology and Venereology, the Second Affiliated Hospital of Anhui Medical University, Hefei 230601, China; 2 Joint Laboratory for Plasma Clinical Applications, the Second Affiliated Hospital of Anhui Medical University, Hefei 230601, China; 3 Department of Dermatology, Peking University Shenzhen Hospital, Shenzhen 518036, China; 4 Institute of Dermatology, Shenzhen Peking University-Hong Kong University of Science and Technology Medical Center, Shenzhen 518036, China; 5 PKU-Shenzhen Clinical Institute of Shantou University Medical College, Shenzhen 518036, China
  • Online:2026-04-15 Published:2026-04-08

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摘要： 化脓性汗腺炎（hidradenitis suppurativa,HS）是一种慢性炎症性疾病，疼痛是其常见症状，严重影响患者的生活质量。HS疼痛机制复杂，兼具伤害感受性、神经病理性及伤害可塑性特征。管理需基于“生物-心理-社会”模式：急性疼痛可采用病灶内注射曲安奈德、非甾体抗炎药及外用制剂；慢性疼痛推荐多模式治疗，如度洛西汀联合普瑞巴林。儿童、妊娠期及老年患者需制定个体化方案。此外，物理治疗、手术干预、伤口护理及心理支持亦不可或缺。本文概述了HS疼痛的发生机制、临床特征和评估方法，以期为优化个体化治疗策略、全面提升患者生活质量提供参考。

关键词: 化脓性汗腺炎, 疼痛管理, 慢性疼痛, 急性疼痛

Abstract: Hidradenitis suppurativa (HS) is a chronic inflammatory disease, and pain is its common symptom that severely impairs patients' quality of life. The pain mechanism of HS is complex, characterized by a combination of nociceptive, neuropathic and nociceptive plasticity features. Its management should be based on the biopsychosocial model: for acute pain, intralesional triamcinolone acetonide injection, non-steroidal anti-inflammatory drugs (NSAIDs) and topical preparations can be administered; for chronic pain, multimodal therapy is recommended, such as duloxetine combined with pregabalin. Individualized regimens are required for pediatric, pregnant and elderly patients. In addition, physical therapy, surgical intervention, wound care and psychological support are also indispensable. This paper summarizes the pathogenesis, clinical characteristics and assessment methods of pain in HS, aiming to provide a reference for optimizing individualized treatment strategies and comprehensively improving patients' quality of life.

Key words: hidradenitis suppurativa, pain management, chronic pain, acute pain