关键词: 丘疹性弹力纤维溶解症, 家族性, 儿童, 皮肤镜, 弹性纤维

Abstract: Familial juvenile papular elastorrhexis (PE) is a rare disease. This paper reports one affected family and reviews relevant literature: the proband was an 11-year-old girl with multiple asymptomatic white papules on the trunk and upper extremities for one year, and her 8-year-old younger sister presented with two similar lesions on the anterior chest, both children were followed up for 6 months after confirmed diagnosis, with no lesion progression and no specific treatment given. We searched Chinese and English literature from database establishment to October 2025 across multiple databases, initially retrieving 58 articles and finally including 15 pepers involving 41 patients, among whom 3 received dermoscopy and 27 underwent histopathological examination combined with special VVG elastic fiber staining. The lesions are characterized by multiple skin-colored or pale white small papules predominantly on the trunk and upper extremities without subjective symptoms; dermoscopy shows central yellow-white structureless areas surrounded by radial pigmentation and no abnormal vessels, while histopathology reveals basically normal epidermis and mild perivascular lymphocytic infiltration in the superficial dermis, and VVG staining indicates fragmentation, reduction or absence of dermal elastic fibers. Given the non-specific clinical manifestations, histopathology is the gold standard for definite diagnosis, and the characteristic dermoscopic findings can act as a non-invasive auxiliary diagnostic tool to improve clinical diagnostic efficiency.

Key words: papular elastorrhexis, familial, child, dermoscopy, elastic fibers