中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (11): 710-712.doi: 10.12144/zgmfskin202111710

• 临床研究 • 上一篇    下一篇

IL-17A单抗治疗儿童泛发性脓疱型银屑病一例并文献复习

王娜,周盛基,冉德林,暴芳芳,施仲香    

  1. 山东第一医科大学附属皮肤病医院(山东省皮肤病医院,山东省皮肤病性病防治研究所),济南,250022
  • 出版日期:2021-11-15 发布日期:2021-09-15
  • 通讯作者: 施仲香,E-mail: szxsd2003@sina.com

Secukinumab successfully treatment of generalized pustular psoriasis in children: a case report and literature review

WANG Na, ZHOU Shengji, RAN Delin, BAO Fangfang, SHI Zhongxiang    

  1. Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University, Jinan 250022, China
  • Online:2021-11-15 Published:2021-09-15
  • Contact: SHI Zhongxiang, E-mail: szxsd2003@sina.com

摘要:

传统药物如甲氨蝶呤,阿维A和环孢菌素A等治疗儿童泛发性脓疱型银屑病(GPP)受到限制,目前没有针对青少年GPP的标准化诊疗指南,本文报道IL-17A单抗成功治疗儿童脓疱型银屑病一例并进行文献复习。

关键词: 脓疱型银屑病, 司库奇尤单抗, 生物制剂

Abstract: The conventional systemic therapy is limited to treatment of juvenile generalized pustular psoriasis (GPP), such as methotrexate, retinoic acid and cyclosporin A. No standardized guidelines are available for juvenile GPP. Herein, we report a case of a 9-year-old girl with GPP successfully treated with secukinumab and review the related literature.

Key words: generalized pustular psoriasis, secukinumab, biologic agent