中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (12): 801-803.doi: 10.12144/zgmfskin202112801

• 病例报告 • 上一篇    下一篇

依奇珠单抗治疗儿童脓疱型银屑病一例

陈祚玺1,2,张园2,赵晴2,施仲香2,孙勇虎2,张福仁2   

  1. 1山东大学齐鲁医学院，山东济南，250012；
    2山东第一医科大学附属皮肤病医院（山东省皮肤病医院），山东省皮肤病性病防治研究所，济南，250022
  • 出版日期:2021-12-15 发布日期:2021-09-29
  • 通讯作者: 张福仁，E-mail: zhangfuren@hotmail.com

Treatment of childhood pustular psoriasis with ixekizumab: a case report

CHEN Zuoxi1,2, ZHANG Yuan2, ZHAO Qing2, SHI Zhongxiang2, SUN Yonghu2, ZHANG Furen2   

  1. 1 Cheeloo College of Medicine, Shandong University, Jinan 250012, China; 
    2 Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2021-12-15 Published:2021-09-29
  • Contact: ZHANG Furen, E-mail: zhangfuren@hotmail.com

PDF (PC)

279

摘要： 有文献报道脓疱型银屑病的发生和发展与IL-17A有关，使用IL-17A拮抗剂可一定程度上逆转银屑病的分子生物学过程，从而改善患者的临床症状。目前有依奇珠单抗治疗成年人脓疱型银屑病的报道，但尚未有其治疗儿童脓疱型银屑病的报道，本文报道依奇珠单抗成功治疗12岁脓疱型银屑病患儿一例。

关键词: 脓疱型银屑病, 儿童, 依奇珠单抗

Abstract: It has been reported that the occurrence and development of pustular psoriasis is related to IL-17A, and IL-17A antagonists can reverse the molecular biological process of psoriasis and improve the clinical symptoms of patients. Ixekizumab has been used to treat pustular psoriasis in adult, but there was no report of ixekizumab in the treatment of the child with pustular psoriasis. We report a case of 12-year-old girl with pustular psoriasis who responds well to ixekizumab treatment.

Key words: pustular psoriasis, childhood, ixekizumab