中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (2): 72-75.doi: 10.12144/zgmfskin202102072

• 论著 • 上一篇    下一篇

792例儿童白癜风临床分析

钱莹莹,李巍,吴亚芬,鲁慧,胡翠,苑春雨,李纪兵,张婷,钱华   

  1. 苏州大学附属儿童医院，苏州，215000
  • 出版日期:2021-02-15 发布日期:2021-02-02
  • 通讯作者: 钱华，E-mail: qianhua721@163.com

Clinical analysis of 792 cases of childhood vitiligo

QIAN Yingying, LI Wei, WU Yafen, LU Hui, HU Cui, YUAN Chunyu, LI Jibing, ZHANG Ting, QIAN Hua   

  1. Children's Hospital of Soochow University, Suzou 215000, China
  • Online:2021-02-15 Published:2021-02-02
  • Contact: QIAN Hua, E-mail: qianhua721@163.com

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摘要： 对792例我院确诊的儿童白癜风病例进行回顾性分析。792例患儿中，男405例（51.14%），女387例，3～8岁患儿589例（74.37%），6岁为发病高峰年龄。最常累及部位为面颈部，共284例（35.86%）。102例（12.88%）有家族史，534例（67.42%）春夏季发病，242例（30.56%）发病前有外伤、精神因素、日晒等诱发因素。113例（14.27%）伴有其他疾病。实验室检查示白癜风组TPOAb阳性43例(9.31%)，TGAb阳性24例 (5.19%)，显著高于正常对照组的1.65%和0.63%（均P<0.05）; 血清25-（OH）D水平为（37.64±13.62）nmol/L明显低于正常对照组的（62.87±12.38）nmol/L，差异具有统计学意义（P<0.05）。治疗有效率为57.38%，面颈部治疗效果优于躯干及四肢。

关键词: 儿童, 白癜风, 临床特征

Abstract: The data of 792 children with vitiligo in our hospital were analyzed. Of 792 patients, 405 were male and 387 were female, the age of the patients ranged from 3 to 8 and the peak age was 6. The most common location was face and neck (284 cases, 35.86%). 102 patients (14.27%) had family history. The high peak was in spring and summer (534 cases, 67.42%). 242 patients (30.56%) had a history of trauma, mental factors, sun exposure and other inducing factors. 113 patients (14.27%) had other diseases. Of 792 patients, TPOAb and TGAb positivity rates were 9.13% and 5.19% respectively in the vitiligo group, which were higher than those in the normal control group (1.65% and 0.63%), with significant differences (Ps<0.05). The serum 25-(OH)D level was (37.64±13.62) nmol/L, which significantly lower than that in the normal control group, with a significant difference (P<0.05). The effective rate of treatment was 57.38% and the efficacy of face and neck was better than that of trunk and limbs. 

Key words: children, vitiligo, clinical features