中国麻风皮肤病杂志 ›› 2022, Vol. 38 ›› Issue (3): 199-202.doi: 10.12144/zgmfskin202203199

• 综述 • 上一篇    

生物制剂在银屑病特殊人群中的应用

陈洁,包军   

  1. 南京医科大学鼓楼临床医学院，南京， 210000
  • 出版日期:2022-03-15 发布日期:2022-01-06
  • 通讯作者: 包军，E-mail: baojun1968@sina.com

Application of biological agents used in China in special population with psoriasis

CHEN Jie, BAO Jun   

  1. Gulou Clinical Medical College of Nanjing Medical University, Nanjing 210000, China
  • Online:2022-03-15 Published:2022-01-06
  • Contact: BAO Jun, E-mail: baojun1968@sina.com

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摘要： 传统的治疗银屑病药物有一定的疗效，但由于其副作用的影响，临床应用在一定范围内受到了限制。生物制剂作为当前研究热点，相比传统药物具有更好的安全性和治疗效果。本文主要讨论目前我国药监局（NMPA）批准使用的银屑病治疗生物制剂在孕妇、哺乳期妇女、儿童、慢性感染患者、恶性肿瘤患者及疫苗接种患者等特殊人群中的应用。

关键词: 银屑病, 生物制剂, 孕妇, 哺乳期妇女, 儿童, 慢性感染, 恶性肿瘤, 疫苗

Abstract: The traditional drugs for the treatment of psoriasis are effective, but their clinical application is limited in some people for the adverse reactions. Biological agents have better safety and efficacy than traditional drugs. The application of several biological agents for the treatment of psoriasis which have been approved by National Medical Products Administration (NMPA) in pregnant women, lactating women, children, patients with chronic infection, patients with malignant tumors, and vaccinated patients is reviewed in this paper.

Key words: psoriasis, biological agents, pregnant women, lactating women, children, chronic infection, malignant tumors, vaccination