中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (5): 371-374.doi: 10.12144/zgmfskin202505371

• 病例报告 • 上一篇    下一篇

透明细胞丘疹病一例

秦国敬1,潘盼2,王丽华1   

  1. 1济南市中心医院皮肤科，山东济南，250013；2济南市中心医院病理科，山东济南，250013
  • 出版日期:2025-05-15 发布日期:2025-05-15

Clear cell papulosis: a case report

QIN Guojing1, PAN Pan2, WANG Lihua1   

  1. 1 Department of Dermatology, Jinan Central Hospital, Jinan 250013, China; 2 Department of Pathology, Jinan Central Hospital, Jinan 250013, China
  • Online:2025-05-15 Published:2025-05-15

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摘要： 透明细胞丘疹病是一种色素减退性皮肤病，发病年龄小，无需特殊治疗，本文报道一例。患者，女，3岁，下腹部散在白色斑疹2年余，皮疹增多1周。组织病理学检查示棘层轻度增厚，基底层色素颗粒减少，可见散在数个透明细胞；免疫组化示CEA、EMA、CK-7均阳性，S100、Melan-A阴性。未予治疗，随访3年余，患儿皮疹全部消退。

关键词: 儿童, 透明细胞丘疹病

Abstract: Clear cell papulosis is a hypopigmentary skin disease that typically affects individuals at a young age and dose not necessitate any special treatment. Herein, we report a 3-year-old girl presented with scattered white macules on the lower abdomen for more than 2 years, which increased for 1 week. Histopathological examination showed mild thickening of the stratum spinosum, with decreased pigmentation in the basal layer and several clear cells scattered throughout. Immunohistochemistry examination showed positive for CEA, EMA, and CK-7, while negative for S-100 and Melan-A. No treatment was given, and all the rashes of the child subsided spontaneously after 3-year follow-up.

Key words: child, clear cell papulosis