中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (11): 807-808.doi: 10.12144/zgmfskin202411807

• 病例报告 • 上一篇    下一篇

手术联合5-盐酸氨基酮戊酸光动力治疗儿童甲周疣一例

孙晓静,柳赛赛,于学红   

  1. 山东大学附属威海市立医院，山东威海，264200
  • 出版日期:2024-11-15 发布日期:2024-10-15

Surgery combined with 5-aminolevulinic acid photodynamic therapy for periungual warts in a child: a case report

SUN Xiaojing, LIU Saisai, YU Xuehong   

  1. Weihai Municipal Hospital, Cheeloo College of Medicine, Shandong University, Weihai 264200, China
  • Online:2024-11-15 Published:2024-10-15

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摘要： 甲周疣常规冷冻治疗常因疼痛和治疗次数多，导致患儿依从性极差，多次治疗也可能导致甲损伤。外科手术可以一次性去除肉眼可见疣体，但无法清除潜在病毒，皮损容易复发。有报道证实5-盐酸氨基酮戊酸光动力治疗可以清除潜在的病毒感染。本文报道一例甲周疣病史3年的患儿，手术去除疣体后，行4次5-氨基酮戊酸光动力治疗，末次治疗后21天创面完全愈合，术后随访半年未见复发。

关键词: 甲周疣, 外科手术, 光动力治疗, 儿童

Abstract: Conventional cryotherapy for periungual warts often leads to poor compliance due to pain and repeated treatments in children, and repeated treatments may also lead to nail injury. Surgery can remove macroscopic warts at one time, but it cannot destroy the latent virus, and the warts are prone to relapse. It has been reported that 5-aminolevulinic acid photodynamic therapy (ALA-PDT) can destroy virus. Herein, we report a child who had a 3-year history of periungual warts. The warts of the patient was surgically removed, and then given 5-ALA-PDT four times. The wound healed 21 days after the last photodynamic therapy. There was no recurrence after six months follow-up.

Key words: periungual warts, surgery, photodynamic therapy, children