Abstract: A 47-year-old female presented with leg petechiae and ecchymosis for 4 months. The symptoms were aggravated after fatigue and bad mood stimulation. Laboratory examination showed an increase in globulin levels and erythrocyte sedimentation rate, strong positivity of rheumoid factor, mild anemia, but normality of platelet counting. SSA/SSB and Schirmer test were positive. The function of salivary glands was decreased. The features of biopsy was in accordance with the diagnosis of sjogren's syndrome. The diagnosis of hyperglobulinemic purpura complicated with Sjogren syndrome was made. There was no recurrence of skin lesions after combined therapy with glucocorticoid, gydroxychloroquine, N-acetylcysteine and paeony during 2 years follow-up.

Key words: hyperglobulinemia purpura, sjogren's syndrome