Abstract: The classification and diagnosis of mastocytosis (MC) were renovated by WHO in 2016. Some new therapies have been used in treating MC, such as tyrosine kinase inhibitor, monoclonal antibody targeted therapy, cell reduction, hematopoietic stem cell transplantation, etc. The classification, pathogenesis, the common and new therapies are reviewed in this article.

Key words: mastocytosis, tyrosine kinase inhibitor, targeted therapy, hematopoietic stem cell transplantation