China Journal of Leprosy and Skin Diseases ›› 2019, Vol. 35 ›› Issue (9): 564-567.doi: 10.12144/zgmfskin201909564

Previous Articles     Next Articles

Update of the pathogenesis and therapeutic mechanism of port wine stain

WANG Meiling1,2, LIU Huaxu2   

  1. 1.School of Medicine and Life Science, Jinan University-Shandong Academy of Medical Sciences, Jinan 250000, China; 2. Shandong Provincial Hospital for Skin Disease & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2019-09-15 Published:2019-09-16
  • Contact: LIU Huaxu, E-mail: liueternal@163.com

PDF (PC)

189

Like

Abstract: Port wine stain (PWS) is a type of common abnormality of capillaries and postcapillary venule. Most of PWS is congenital, with a prevalence of 3/1000-5/1000. Pulsed dye laser is the first choice for the treatment of PWS, but the efficacy is not ideal due to the fact that some blood vessels cannot be fully closed, and some blood vessels will get recanalization and reperfusion after treatment. The pathogenesis, therapeutic mechanism and the mechanism of angiogenesis after treatment of PWS were reviewed in the paper.

Key words: port wine stain, mechanism, angiogenesis inhibitors