China Journal of Leprosy and Skin Diseases ›› 2021, Vol. 37 ›› Issue (2): 88-91.doi: 10.12144/zgmfskin202102088

• Original Articles • Previous Articles     Next Articles

Linear IgA/IgG bullous dermatosis of childhood: a case report

CHEN Zuoxi1,2, YU Changping2, WANG Na2, SHI Zhongxiang2, ZHOU Guizhi2, MI Zihao2, ZHANG Furen2   

  1. 1 Cheeloo College of Medicine, Shandong University, Jinan 250012, China; 2 Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University, Jinan 250022, China
  • Online:2021-02-15 Published:2021-02-02
  • Contact: ZHANG Furen, E-mail: zhangfuren@hotmail.com

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Abstract: A 7-year-old boy presented with pruritic erythema and vesicular on his trunk and extremities for two months. He had a history of heavy sun exposure. Histopathology of vesicular revealed  subepidermal blister, microabscess composed of neutrophils and a few eosinophils in the dermal papillary and an inflammatory infiltrate of neutrophils, eosinophils and lymphocytes in the superficial dermis. Indirect IF using 1 M NaCl-split-normal human skin showed IgA and IgG autoantibodies deposited on the epidermal site. In addition, IgG autoantibody was also deposited on the dermal. The diagnosis of linear IgA/IgG bullous dermatosis of childhood was made. The patient was treated with methylprednisolone, dapsone, intravenous immunoglobulin and mycophenolate sodium and the condition was improved obviously.

Key words: linear IgA/IgG bullous dermatosisof childhood, ultraviolet