China Journal of Leprosy and Skin Diseases ›› 2022, Vol. 38 ›› Issue (4): 232-235.doi: 10.12144/zgmfskin202204232

• Clinical Researches • Previous Articles     Next Articles

Reactive cutaneous capillary endothelial proliferation caused by PD-1 inhibitor camrelizumab: two cases report

ZHANG Qianqian1, QI Zhaoliang2, YANG Hui1, WANG Xiaoyan3   

  1. 1 Department of Dermatology, 960 Hospital of Chinese PLA, Taian 271000, China; 2 Department of Respiratory, 960 Hospital of Chinese PLA, Taian 271000, China; 3 Department of Pathology, 960 Hospital of Chinese PLA, Taian 271000, China
  • Online:2022-04-15 Published:2022-02-10
  • Contact: QI Zhaoliang, E-mail: zhaoliang_qi@163.com

Abstract: Two patients with lung cancers presented with cutaneous capillary endothelial proliferation on the head, face, trunk, and extremities after the first treatment with camrelizumab for 2 or 3 weeks. Some lesions which were accompanied with ulceration and bleeding were treated with surgical resections. The histological feature was in accordance with granulomatous hemangioma. The diagnosis of reactive cutaneous capillary endothelial proliferation was made.

Key words: camrelizumab, PD-1 inhibitor, reactive cutaneous capillary endothelial proliferation, Immune-related adverse events