China Journal of Leprosy and Skin Diseases ›› 2022, Vol. 38 ›› Issue (4): 236-237.doi: 10.12144/zgmfskin202204236

• Case Reports • Previous Articles     Next Articles

Skin phototoxicity induced by pirfenidone: a case report

LI Jun1,2, ZHANG Litao2   

  1. 1 Tianjin University of Traditional Chinese Medicin，Tianjin 301617，China;
    2 Department of Dermatology，Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital，Tianjin 300120，China
  • Online:2022-04-15 Published:2022-02-10
  • Contact: ZHANG Litao, E-mail: zhanglitao@medmail.com.cn

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Abstract: Pirfenidone is a new broad-spectrum anti-inflammatory and anti-fibrosis drug, which has a very good effect on idiopathic pulmonary fibrosis. But it also has more adverse reactions, such as photosensitivity. We report a case of pulmonary fibrosis with severe phototoxicity after 4 weeks of pirfenidone treatment in this paper. The skin lesions gradually subside after pirfenidone was discontinued and glucocorticoid was given.

Key words: pirfenidone, phototoxic reaction, glucocorticoids