Abstract: Objective: To analyze the infection status of Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), Ureaplasma uyticum (UU) in patients with suspected genitourinary system infection in our hospital. Methods: Data of 2660 patients (758 females and 1902 males) admitted to our hospital from January 2020 to March 2023 were retrospectively analyzed. The infection rates of NG, CT and UU were compared among in patients with different sex, age and sampling sites. Results: Among 2660 patients, the highest positivity rate was UU (34.55%), followed by CT (11.92%) and NG (11.54%). Among 1902 male and 758 female patients, the infection rates of NG, CT and UU were 14.56% and 4.96%, 11.88% and 12.01%, 21.24% and 67.94%, respectively. There were significantly differents of positivity rates of NG and UU between male and female (Ps<0.05). The mixed infection rate was 8.72%, including NG+CT of 1.80%, CT+UU of 4.69%, NG+UU of 1.20%, NG+CT+UU of 1.01%. The infection rate of NG, CT and UU was the highest in the age group ≤20 years old, and the infection rate of NG, CT and UU decreased with the increase of age. Among 1902 infected male, 1346 cases had urethra infection and 166 had glans infection. NG, CT, UU urethral infection and glans infection were 13.37% and 7.22%, 10.69% and 7.22%, 18.13% and 30.12%, respectively. There was a significant difference of NG and UU infection rate betwteen urethra and glans (P<0.05). Among 758 female, 7738 had cervical infection and 46 had vulva infection. The infection rates of NG, CT and UU of cervix and vulva were 2.98% and 4.35%, 6.77% and 26.08%, 73.44% and 86.96%, respectively. There was a significant difference of CT and UU infection rate between cervix and vulva. Conclusion: In this study, the infection rate of UU was the highest in patients with genitourinary system infection. The males were susceptible to NG infection and famles were susceptible to UU infection.

Key words: sexually transmitted diseases, Neisseria gonorrhoeae, Chlamydia trachomatis, Ureaplasma uyticum