China Journal of Leprosy and Skin Diseases ›› 2021, Vol. 37 ›› Issue (10): 676-678.doi: 10.12144/zgmfskin202110676

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The role of exosomes in the immune regulation of infectious diseases

XIE Jiahao1, CHEN Jialing1, HUANG Zheng1, ZOU Ruitao1, CAI Guiyue1, CHEN Rongyi1, WANG Liuyuan2   

  1. 1 Guangdong Medical University & Affiliated Hospital of Guangdong Medical University, Zhanjiang 524000, China; 2 Dermatology Hospital, Southern Medical University, Guangzhou 510095, China
  • Online:2021-10-25 Published:2021-09-01
  • Contact: WANG Liuyuan, E-mail: qqmaomaochong@163.com;CHEN Rongyi, E-mail: rongyichen@163.com

Abstract: Exosomes are double-layered vesicles based on the inner cell membrane, with various components related to biology and pathology. Exosomes exist in a variety of body fluids, containing a variety of DNA and mRNA fragments, non-coding RNA molecules, proteins and lipids and other biological molecules. They play an important role in cell information transmission and participate in a variety of pathophysiological processes, such as apoptosis, angiogenesis, immune regulation, tumor migration, etc. The role of exosomes in the immune regulation of infectious diseases is reviewed in this article.

Key words: exosomes, sexually transmitted diseases, infection, immunomodulatory, microRNA