Abstract: It has been found that MiRNAs (miRNAs) play an important role in the pathogenesis of psoriasis in recent years such as regulating T cells, cytokines, innate immunity, and the proliferation and differentiation of keratinocytes and skin barrier function. MicroRNAs are stable in both serum and tissues and may be used as new markers for psoriasis diagnosis, the disease severity assessment, monitoring therapy response and predicting prognosis in the future. The update of MicroRNAs in the pathogenesis of psoriasis is reviewed in this paper.

Key words: psoriasis, MicroRNAs