Abstract: Pseudoepitheliomatous granuloma is a kind of abnormal proliferation of reactive epithelial cells, which is secondary to trauma, inflammation or infection. Pseudepithelioma-like lesions secondary to burn wounds are rare. The two patients in this paper were both induced by topical application of traditional Chinese medicine preparations, with a “cauliflower-like” appearance, similar to malignant tumors, and easy to be misdiagnosed. The wound was closed 2 weeks after surgery by complete debridement combined with thick split thickness skin graft.

Key words: pseudoepitheliomatous granuloma, burns, skin grafting