China Journal of Leprosy and Skin Diseases ›› 2016, Vol. 32 ›› Issue (4): 248-250.

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The role of Th17 cells in the pathogenesis of non-segmental vitiligo

CAO Yan1，WANG Guangping2，WANG Lin1, JIA Hong2, YANG Xueyuan2.   

  1. 1.Nanjing University of Chinese Medicine，Nanjing210046，China; 2. Institute of Dermatology，Chinese Academy of Medical Sciences, Nanjing 210042,China
  • Online:2016-04-15 Published:2018-12-24

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Abstract: Currently the most recognized mechanism of non-segmental vitiligo is autoimmune dysregulation. Th17 cells as CD4 + T helper T cell (Th cell) subset, can break immune tolerance, lead to autoimmune destruction of melanocytes and play an important role in the pathogenesis of vitiligo. In this paper the role of Th17 cells in the pathogenesis of vitiligo is reviewed.

Key words: non-segmental vitiligo, Th17