China Journal of Leprosy and Skin Diseases ›› 2016, Vol. 32 ›› Issue (6): 339-341.

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Detection of the levels of vitamin D and some acute phase response pattern in the patients with chronic spontaneous urticaria

MA Yiping,LI Chengrang,WU Jianbing, CUI Pangen, LIN Lin.   

  1. Institute of Dermatology, Chinese Academy of Medical Sciences, Nanjing 210042，China
  • Online:2016-06-15 Published:2018-12-27
  • Contact: MA Yiping, E-mail: mayipingg@sohu.com

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Abstract: Objective: To determine the relationship among vitamin D level, and C3, C4 and CRP concentrations and the disease severity of chronic spontaneous urticaria. Methods: Concentrations of CRP, C3, C4 and 25-hydroxyvitamin D [25(OH) D] were detected in 55 patients and 30 healthy controls. The disease severity score (UAS7) was assessed clinically. Results: The level of serum 25(OH) D in CSU patients was significantly lower than that in controls and the concentrations of CRP, C3 and C4 were significantly higher than those in controls. There was a negative correlation between the level of 25(OH) D and UAS7 score in the patients and there was no correlation between the levels of 25(OH) D, and the concentration of CRP, C3 and C4. Conclusion: The serum level of 25(OH) D is associated with the severity of CSU.

Key words: urticaria, vitamin D, complement