China Journal of Leprosy and Skin Diseases ›› 2017, Vol. 33 ›› Issue (6): 337-340.

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Mottled hypopigmentation induced by Q-switched 1064 nm Nd:YAG laser in the treatment of melasma: a two-years follow-up study

WANG Yan1*, GAO Lei2*, ZHANG Qian3, XU Li4, DU Xiaojing5.   

  1. 1. Wuxi Sharm Plastic Hospital, Wuxi 214000, China; 
    2. Gaoxinchang Clinic, Jieshou 236501, China; 
    3. Maternal and child health care hospital of Huangdao District,Qingdao 266400, China; 
    4. Jinan Central Hospital , Jinan 250002, China; 
    5. The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250001, China
  • Online:2017-06-15 Published:2018-12-13
  • Contact: DU Xiaojing, E-mail: 13573778877@163.com

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Abstract: Objective: To investigate the development of the mottled hypopigmentation induced by low-fluence large-spot-size Q-switched 1064 nm Nd:YAG laser in the treatment of melasma. Methods: One hundred and eighty patients with melasma treated with the Q-switched 1064 nm Nd:YAG laser for more than 5 times were followed up for 2 years. Results: Out of 180 patients with melasma, fifteen patients (8.33%) presented with mottled hopopigmentation. The hypopigmentation lesions recoveried in one case after 2 years, improvement in 2 and no change in 13. Conclusion: The mottled hypopigmentation induced by the low-fluence large-spot-size Q-switched 1064 nm Nd:YAG laser can persist for more than two years.

Key words: low-fluence large-spot-size Q-switched 1064 nm Nd:YAG laser, melasma, mottled hypopigmentation