China Journal of Leprosy and Skin Diseases ›› 2017, Vol. 33 ›› Issue (7): 440-443.

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Update of the mechanism of dendritic cells regulated by SOCS in inflammatory diseases

LI Tianhang, SHI Dongmei.   

  1. 1. Department of Dermatology, Jining NO.1 People's Hospital, Jining 272001, Shandong, China; 2. Department of Mycology, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, 210042, Nanjing, China
  • Online:2017-07-15 Published:2018-12-03
  • Contact: SHI Dongmei, E-mail: shidongmei28@163.com

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Abstract: Cytokine signaling suppressive gene plays an important role in the development of inflammatory diseases, through regulating the balance of the immune response, and differentiation and maturation of the dendritic cells. This article reviews the recent researches on the mechanism of dendritic cells regulated by SOCS in psoriasis, rheumatoid arthritis, systemic lupus erythematosus and fungal infection.

Key words: suppressor of cytokine signaling, dendritic cells, regulate, inflammatory disease