Abstract: Objective: To determine the incidence and risk factors of contact dermatitis caused by transparent dressing after peripherally inserted central catheters (PICCs) catheterization in 972 patients with malignant tumor. Methods: The risk factors of contact dermatitis were analyzed by univariate and multivariate logistic regression analysis, including gender, age, body mass index, cTNM stage, history of drug allergy, tumor type, and the levels of eosinophils and basophils in peripheral blood. Results: Of 972 patients, 80 patients (21 males and 59 females) suffered from contact dermatitis caused by transparent dressing after PICCs. The incidence of contact dermatitis was 8.23%. Univariate analysis showed that eosinophil count, sleep status, body mass index and drug allergy history were associated with contact dermatitis (P＜0.05). Multivariate logistic regression analysis showed that insomnia, obesity and drug allergy were independent risk factors for contact dermatitis（P＜0.001）. Conclusion: The incidence of contact dermatitis caused by transparent dressings is high. Insomnia, obesity and drug allergy history are the independent risk factors for the contact dermatitis caused by transparent dressings after PICCs.

Key words: peripherally inserted central catheter, malignant tumor, contact dermatitis, transparent dressing