Abstract: Objective: To analyze the allergen test results of 3793 patients with allergic dermatoses from the Dermatology Hospital Affiliated to Shandong First Medical University, investigate the distribution of allergens across different age groups and disease types, and provide reference for the clinical diagnosis and treatment of allergic dermatoses. Methods: A retrospective analysis was conducted on the test results and clinical data of 3793 patients with allergic dermatoses who visited the hospital from February 2023 to April 2024. Serum total IgE (tIgE) and specific IgE (sIgE) were detected using the Phadia 250 ImmunoCAP System. Results: Among the 3793 patients with allergic dermatoses, the differences in the incidence rates of eczema, atopic dermatitis, and urticaria across different genders and age groups were statistically significant (P＜0.05). The positivity rates of tIgE for eczema, atopic dermatitis, and urticaria were 49.7%, 66.7%, and 70%, respectively, with statistically significant differences among the groups (P＜0.05). The positivity rates of various types of sIgE also showed statistically significant differences (Ps＜0.05). Among the preschool group, school-age group, and adult group, there were statistically significant differences in the positivity rates of tIgE, mixed food, Phadiatop, protein, milk, shrimp, wheat, peanut, mixed nuts, dermatophagoides pteronyssinus, dermatophagoides farinae, mixed molds, mixed animal dander, mixed weed pollen, mixed tree pollen, and mixed house dust (Ps＜0.05). Conclusion: The distribution of allergens varies significantly among patients of different ages and with different allergic dermatoses. The detection rate of inhalant allergens was significantly higher in school-age children, while the detection rate of ingestant allergens was significantly higher in preschool children.

Key words: allergic dermatoses, specific IgE, allergen